Parkinson’s disease (PD) is a progressive neurological disorder that affects movement. It develops gradually, often starting with a barely noticeable tremor in one hand.
The condition is caused by the loss of nerve cells in the part of the brain called the substantia nigra, which produces dopamine. Dopamine is a chemical messenger crucial for smooth, coordinated muscle function.
A lack of dopamine leads to the primary motor symptoms of PD, including tremor, rigidity (stiffness), bradykinesia (slowness of movement), and postural instability (impaired balance).
Currently, there is no single definitive test for Parkinson’s disease. Diagnosis is primarily clinical, meaning it is based on a detailed medical history, a review of symptoms, and a thorough neurological and physical examination performed by a specialist, typically a neurologist or a movement disorders specialist.
The doctor will look for the characteristic motor symptoms. They may ask the patient to perform simple tasks like walking, writing, or tapping their fingers to assess movement, rigidity, and coordination. Blood tests and imaging scans (like MRI) may be used to rule out other conditions that can mimic Parkinson’s symptoms.
In some uncertain cases, a specialist may use a dopamine transporter (DaT) scan, which can visualize the brain’s dopamine system, or may observe the patient’s response to Parkinson’s medications to help confirm the diagnosis.
Because symptoms often start subtly, a diagnosis can sometimes take time to confirm, with specialists often recommending regular follow-up appointments.
Receiving a diagnosis of Parkinson’s can evoke a wide range of intense emotions, including shock, denial, anxiety, anger, or even a strange sense of relief at finally having an explanation for unexplained symptoms. This is a life-changing event, and taking time to process the news is essential.
The diagnosis marks the start of a proactive journey in managing the condition:
A diagnosis of Parkinson’s is not an endpoint; it is the beginning of a new journey defined by management, adaptation, and resilience.
By taking a proactive approach—seeking expert care, adhering to treatment, committing to exercise, and building a strong support system—individuals can work to maintain their quality of life and continue to live well with the condition.
Dr. Navin Tiwari
Consulting Neurologist